BioSpring is a world leading contract manufacturing organization (CMO) for synthetic nucleic acids in the field of oligonucleotide-based commercial therapies, clinical therapeutic development, as well as diagnostics and R&D.
Since 1997, BioSpring provides high-quality products and services under cGMP to the pharmaceutical and biotech industry worldwide.
Located in Frankfurt, Germany, BioSpring’s cGMP-certified and FDA/EMA-inspected facilities offer manufacturing capacity of multiple hundred kilograms per year, including dedicated commercial manufacturing suits and state-of-the art commercial analytical laboratories.
Driven by technology and science, BioSpring’s team is developing innovative manufacturing processes and (bio)-analytical methods to contribute to the future of health in the field of oligonucleotide-based therapies, vaccines, and diagnostics.
Nitto Denko Avecia Inc.
Oligonucleotides are giving rise to a new generation of therapeutics, and Nitto Avecia is helping lead the way. With more than 25 years’ experience in oligonucleotide development and manufacturing, Nitto Avecia is the partner of choice for pharmaceutical innovators creating new drugs with the power to transform treatment for a wide range of diseases. With the capabilities of Nitto Avecia Pharma Services, Nitto Avecia now offers a comprehensive, end-to-end oligonucleotide solution. This offers the advantage of a single, expert partner handling the entire process from Drug Substance through Drug Product manufacturing with flexible solutions and consistent reliability and quality.
Novasep Equipment Solutions
Purification solutions for the pharmaceutical and biopharmaceutical industries – From Process Development to Manufacturing
From the development stage right up to industrial scaling, we provide a complementary range of GMP equipment and services for purification. Modular and customizable, our chromatography equipment can integrate seamlessly into any process.
Operating both as a drug substance producer and an equipment supplier, Novasep has deep insight into the challenges and performance drivers of pharmaceutical and biopharmaceutical manufacturing: time to market, minimizing cost of goods (CoG), quality control, recipe management, monitoring strategy, to name a few.
Bachem is a leading, innovation-driven company specializing in the development and manufacture of peptides and oligonucleotides. With 50 years of experience and expertise Bachem provides products for research, clinical development and commercial application to pharmaceutical and biotechnology companies worldwide and offers a comprehensive range of services. Bachem operates internationally with headquarters in Switzerland and locations in Europe, the US and Asia. The company is listed on the SIX Swiss Exchange.
Gyros Protein Technologies
Gyros Protein Technologies, enables peptide synthesis and bioanalytical solutions that help scientists increase biomolecule performance and productivity in research, drug discovery, pre-clinical and clinical development, and bioprocess applications. Our low- to mid-scale peptide synthesizer platforms are PurePep™ Chorus, Tribute®, Prelude® X, Symphony® X, and Sonata® XT. These solutions and our chemistries deliver uncompromising purity, flexibility, and quality for discovery and pre-clinical studies of simple to complex multifunctional peptides. Gyros Protein Technologies is a division of Mesa Laboratories.
The PolyPeptide Group is a privately-held group of manufacturing sites which focus on proprietary and generic GMP-grade peptides for the pharmaceutical and biotechnological market. With more than 60 years of experience, the Group is committed to the highest quality of peptide manufacturing for commercial peptide drug substances, GMP peptides in clinical trials, or small-scale non-GMP custom syntheses.
The Group has manufacturing facilities in Belgium (Braine L’Alleud), Sweden (Malmo), France (Strasbourg), India (Ambernath) and two sites in the USA (San Diego CA & Torrance CA). As a multinational company with about 800 employees worldwide, its diversity brings breadth and depth of knowledge and experience to the Group.
The Group's long-established core strength in GMP manufacturing and broad range of services supports peptide & peptide-like projects, including conjugation to non-peptide moieties, from the bench through to commercialization. With continually increasing capacity for GMP manufacturing, the PolyPeptide Group is stronger and better equipped to serve the needs of its customers at all stages of pharmaceutical peptide development. With its multinational organization, strict focus on peptides and solid financial base, the Group offers an almost unique security of supply to its customers.
Purolite® Life Sciences
Purolite Life Sciences brings Purolite’s innovative thinking and distinguished history of resin technology expertise to the global Life Sciences marketplace. Over three decades, Purolite has grown into the world’s premier resin technology manufacturer and innovation leader, with production plants and advanced research labs across the globe.
Purolite Life Sciences provides API’s, enzyme carriers and immobilized enzymes, and resins for purification and separation to support research and development, and production-scale applications in pharmaceuticals, protein purification, food production, bioprocessing, fine chemical and additional markets. With a team of world-class researchers and scientists, we develop novel, high-demand and customized products to meet customer needs.
Tosoh Bioscience is an acknowledged global leader in the field of liquid chromatography with a strong focus on bioseparations. We offer solutions for research, drug discovery, clinical chemistry, environmental analysis, manufacturing and other industrial applications.
Tosoh's portfolio of over 500 specialty products encompasses a comprehensive line of chromatographic media, HPLC columns, and GPC instruments. We can help to analyse and purify any protein, peptide, nucleic acid, antibiotic, or small molecule. Based on existing resins we are also able to develop customized products.
Founded in 1999, Asymchem is a leading global integrated Contract Development and Manufacturing Organization (CDMO) providing innovative drug R&D and manufacturing. Asymchem is supported by 5000 employees based in PR China, the US, and the EU. Our mission is to drive efficiency through continuous technological advances for smarter, greener and more cost-effective manufacturing to support pharmaceutical clinical research and commercialization, backed by a proven track record of successful agency and industry inspections.
Iris Biotech is providing high quality products for the fields peptide synthesis, linkerology, drug delivery, and life sciences in flexible quantities from research scale to commercial production, for academia as well as industry.
Besides our broad portfolio from standard to exotic, we have the know-how and facilities to manufacture your compound of choice based on a Custom Synthesis.
All our services are rounded off by a strong and competent personnel customer support.
We are in continuous exchange with scientists all around the world to gather ideas and be ahead regarding technologies and innovations true to our slogan Empowering Peptide Innovation.
Vapourtec Ltd is a leading flow chemistry manufacturer located near Cambridge, UK. Vapourtec recently launched the revolutionary Variable Bed Flow Reactor (VBFR) to enable continuous flow-SPPS. The VBFR was designed to maintain constant packing density of the solid media, preventing channelling, and improving the efficiency of each coupling and deprotection. The quality of live data (UV and volume change) enables the identification of challenging sequences allowing action to be taken before the next reaction starts. Peptide synthesis can be automated in different scales, from 100 mg of resin to a couple of grams.
IN COLLABORATION WITH
IN COLLABORATION WITH
University of Barcelona
The University of Barcelona is the most formidable public institution of higher education in Catalonia, catering to the needs of the greatest number of students and delivering the broadest and most comprehensive offering in higher educational courses. The UB is also the principal centre of university research in Spain and has become a European benchmark for research activity, both in terms of the number of research programmes it conducts and the excellence these have achieved.
Its own history closely tied to the history of Barcelona and of Catalonia, our university combines the values of tradition with its position as an institution dedicated to innovation and teaching excellence: a university that is as outward-looking and cosmopolitan as the city from which it takes its name.
IN COLLABORATION WITH
University of Milan
The University of Milan, founded in 1924, is a public institution that has a proactive role in science, technology and economics networks. It was one LERU co-founders and is the only Italian University to be a member of the organisation. The University of Milan is involved in several national and international research programs and has also strengthened its efforts to promote technology transfer, a growth area offering exciting new changes and challenges. The results of its research, attested to by an important quantity of scientific publications, have allowed it to obtain the top positions in the most authoritative international rankings. The research at the Department of Pharmaceutical Sciences covers a range of activities focused on the design, synthesis, development, and control of novel biologically active molecules, and of new pharmaceutical drug delivery systems, food supplements, cosmetics, biocides and medical devices. The goals are those of improving knowledge in the field of basic research, a major cultural investment to design a qualified research aimed at the discovery of novel drugs and able to boost an efficient technology transfer.
IN COLLABORATION WITH
Politecnico di Milano
Politecnico di Milano, founded in 1863, is a scientific-technological university which trains engineers, architects and industrial designers. The University has always focused on the quality and innovation of its teaching and research, developing a fruitful relationship with business and productive world by means of experimental research and technological transfer. Research has always been linked to didactics and it is a priority commitment which has allowed Politecnico Milano to achieve high quality results at an international level as to join the university to the business world. Research constitutes a parallel path to that formed by cooperation and alliances with the industrial system. Dipartimento di Chimica, Materiali e Ingegneria Chimica “Giulio Natta” (DCMIC) is the center of the “chemical culture” within the Politecnico di Milano. The DCMIC mission is to conduct high-quality research in the fields of chemistry, chemical engineering, science and materials engineering and bioengineering, promoting their central role in all the new technologies involving matter and energy transformation. Nanomedicine, drug delivery, biomaterials and technologies, pharmaceutical processes are among core interests at DCMIC.