Loading...
Agenda
See our peptides and oligonucleotides tracks: click here below
TRACK ON OLIGOS
8:50 – 9:05
Welcome
Azalea room
9:05 – 09:50
Keynote Lecture
LNA Building Blocks for Therapeutic Oligonucleotides
Jesper Wengel
University of Southern Denmark
09:50 – 10:40
Workshop on Discovery
Oligonucleotide Drug Discovery and Optimization: Case Studies from 15 Years of LNA Drug Design
Christoph Rosenbohm
Roche Denmark
10:40 – 11:00
CMC Considerations for mRNA based Therapeutics
Jo-Anne Riley
Intertek
11:00 – 11:40
COFFEE – POSTERS & EXHIBITION
11:40 – 12:10
Tackling the Challenge of Delivery for Antisense Oligonucleotides
Suzan Hammond
University of Oxford
12:10 – 13:00
Workshop on Manufacturing
Thomas Rupp
Thomas Rupp Consulting
13:00 – 14:00
LUNCH – POSTERS & EXHIBITION
14:00 – 14:20
Pilot and Production Scale Oligonucleotide Synthesis: Overcoming the challenges of polystyrene resin through a novel synthesis method
Hanson Chang
CS BIO
14:20 – 15:10
Workshop on Analytical
Analytical Analysis of Oligonucleotide APIs
Ed Huber
Nitto Denko Avecia
15:10 – 15:40
Roundtable
Oligo Drug Development
Moderator:
Arthur Krieg
Kathryn Ackley
15:40 – 16:20
COFFEE – POSTERS & EXHIBITION
16:20 – 17:05
Keynote Lecture
Regulatory Challenges in Oligonucleotide Drug Development using the Example of BC 007, neutralizer of Pathogenic Autoantibodies against G Protein-Coupled Receptors for Autoimmune-Associated Heart Failure
Annekathrin Haberland
Berlin Cures
17:05 – 17:30
Market Overview: Developments of an Advancing Oligonucleotide Therapeutics Pipeline
Detlef Rethage
Rethage Advisors
17:30 – 19:00
NETWORKING COCKTAIL RECEPTION – POSTERS & EXHIBITION
20:00 – 22:30
NETWORKING DINNER @ La casa dei ciliegi (walking distance)
For registered attendees only
8:50 – 8:55
Welcome
Detlef Rethage
Kathryn Ackley
8:55 – 9:40
Keynote Lecture
Mechanisms and Therapeutic Applications of Immune Stimulatory CpG DNA
Arthur M. Krieg
Checkmate Pharmaceuticals
9:40 – 10:10
Targeting Dynamin 2 in Centronuclear Myopathies with Antisense Oligonucleotides: Pathogenesis and Therapies
Belinda Cowling
Dynacure SAS
10:10 – 10:40
CMC Challenges Associated with Oligonucleotide Products for Local Administration
Bianca Mathee
ProQR Therapeutics N.V.
10:40 – 11:00
Investigator Talks
Kathryn Ackley
11:00 – 11:40
COFFEE – POSTERS & EXHIBITION
11:40 – 12:10
Multitargeting Spherical Nucleic Acids: Advantages & Applications
Matthias Schroff
Exicure
12:10 – 12:30
Manufacturing and process control of modified double stranded oligonucleotides
Manuela Fichte
BioSpring
12:30 – 12:50
Challenges and Considerations in Designing a Large-Scale Solvent Facility for Oligos
Derek Levison
emp Biotech
12:50 – 14:00
LUNCH – POSTERS & EXHIBITION
14:00 – 15:00
Panel Discussion
CDMO News Flashlight
Moderator:
Detlef Rethage
15:00 – 15:30
Regulatory CMC Strategies for Addressing Recent Agency Questions for Clinical and Commercial Stage Oligonucleotides
Jennifer Franklin
Ionis Pharmaceuticals
15:30 – 16:00
Oligonucleotide Manufacturing Capacity of CMO’s. How Much is Enough?
Detlef Rethage
Rethage Advisors
16:00 – 16:15
Final Discussion & Symposium Conclusion
Detlef Rethage
Kathryn Ackley
TRACK ON PEPTIDES
8:50 – 9:05
Welcome
Azalea room
9:05 – 9:50
Keynote Lecture
Peptide Therapeutics Market Trends
Frank Otto Gombert
GPRS – Gombert Pharma Research Solutions
9:50 – 10:20
How to Manage Oral Bioavailability for Cyclic Peptides
Thomas Vorherr
Novartis
10:20 – 10:40
Biological Assays: Responding to Increasing Demands in the Release
of Peptide-Based APIs
Michael Postlethwaite
Bachem
10:40 – 11:00
Investigators Talks
Sara Pellegrino
University of Milan
11:00 – 11:40
COFFEE – POSTERS & EXHIBITION
Workshop on Manufacturing – Moderator: Fernando Albericio
11:40 – 12:10
Production of Peptide via Recombinant Approach. Advantages and Disadvantages from the Economic, Quality and Regulatory Point of View
Piera Fonte
Olon
12:10 – 12:40
Synthesis of Linaclotide Peptide as an Example of a Complex Peptide for Commercial Large Scale Production-Case Study for Small and Commercial Production
Daniel Bourgin
Dr. Reddy’s CPS
12:40 – 13:00
Manufacturing NeoAntigen Peptides: Requirements and Pragmatism
Trishul Shah
Polypeptide Group
13:00 – 14:00
LUNCH – POSTERS & EXHIBITION
14:00 – 14:20
Large Scale Peptide Production via Microwave
Giorgio Marini
CEM
14:20 – 14:40
Are All Resins in Fact the Same? Examining the Advances and Challenges in Peptide Purification and Solid Phase Peptide Synthesis.
Alessandra Basso
Purolite
14:40 – 15:00
Fmoc-Cys(Msbh) – A Sophisticated Building Block for Cysteine-Rich Peptides. A Journey from Discovery to Large Scale Production
Markus Weishaupt
Iris Biotech
15:00 – 15:20
Cost Effective Peptide Purification via ZEOsphere DRP Mixed-Mode Chromatography
Victoria Custodis
Zeochem
15:20 – 15:40
Rapid solution-phase synthetic approach AJIPHASE® for large scale manufacturing
Daisuke Takahashi
Ajinomoto
15:40 – 16:20
COFFEE – POSTERS & EXHIBITION
16:20 – 16:50
Overcoming Challenges to Effect Best Case Technology Transfer
Ewa Kowalska
Ipsen Manufacturing
16:50 – 17:20
Cyclic Peptides with Therapeutic Activity
Fernando Albericio
University of Barcelona
17:20 – 17:30
Investigators Talks
Sara Pellegrino
Chairman
17:30 – 19:00
Networking Cocktail Reception – POSTERS & EXHIBITION
20:00 – 22:30
Networking Dinner @ La casa dei ciliegi (walking distance)
For registered attendees only
8:50 – 8:55
Welcome
Fernando Albericio
Anna Maria Papini
8:55 – 9:40
Keynote Lecture
Radiolabelled Peptides for Cancer Imaging and Therapy: Past-Present-Future
Melpomeni Fani
University Hospital Basel
9:40 – 10:25
Keynote Lecture
Halogenation controls structures and functions of supramolecular peptide assemblies
Pierangelo Metrangolo
Politecnico of Milan
10:25 – 10:45
Challenges in Peptide & Oligonucleotide Formulation: An Integrated CDMO Perspective
Fabio Stevanon
Umberto Romeo
CordenPharma
10:45 – 11:00
Investigators Talks
Sara Pellegrino
University of Milan
11:00 – 11:40
COFFEE – POSTERS & EXHIBITION
Workshop on Delivery – Moderator: Anna Maria Papini
11:40 – 12:10
Specific Glycosylation Techniques for Efficient Protein Therapeutics
Anna Maria Papini
University of Florence
12:10 – 12:40
Drug Delivery
Multimodal PSMA ligand for targeted photodynamic therapy of PSMA-expressing tumors
Dennis Lowik
Radboud University Nijmegen
12:40 – 13:10
Appropriate Screening for ADME Properties and Pseudo-Allergic Reactions Is Key to Success in Peptide Drug Discovery: a Case Study
Elisabetta Bianchi
IRBM
13:10 – 14:00
LUNCH – POSTERS & EXHIBITION
14:00 – 14:45
Regulatory Lecture
Speaker TBC
14:45 – 16:00
Panel and Q&A
Round Table Academy and Industry
Fernando Albericio, Anna Maria Papini, Sara Pellegrino, Silvana Cappelletti, Thomas Vorherr
16:00 – 16:15
Final Discussion & Investigators Conclusion
Fernando Albericio
Anna Maria Papini